Radiation treatment for patients with lung cancer represents a balancing act, particularly if malignant lesions are centrally located near to critical structures. The radiation may destroy the tumour, but vital organs may be seriously damaged as well.

The standard treatment for non-small cell lung cancer (NSCLC) is stereotactic ablative body radiotherapy (SABR), which delivers intense radiation doses in just a few treatment sessions and achieves excellent local control. For ultracentral lung legions, however – defined as having a planning target volume (PTV) that abuts or overlaps the proximal bronchial tree, oesophagus or pulmonary vessels – the high risk of severe radiation toxicity makes SABR highly challenging.

A research team at GenesisCare UK, an independent cancer care provider operating nine treatment centres in the UK, has now demonstrated that stereotactic MR-guided adaptive radiotherapy (SMART)-based SABR may be a safer and more effective option for treating ultracentral metastatic lesions in patients with histologically confirmed NSCLC. They report their findings in Advances in Radiation Oncology.

SMART uses diagnostic-quality MR scans to provide real-time imaging, 3D multiplanar soft-tissue tracking and automated beam control of an advanced linear accelerator. The idea is to use daily online volume adaptation and plan re-optimization to account for any changes in tumour size and position relative to organs-at-risk (OAR). Real-time imaging enables treatment in breath-hold with gated beam delivery (automatically pausing delivery if the target moves outside a defined boundary), eliminating the need for an internal target volume and enabling smaller PTV margins.

The approach offers potential to enhance treatment precision and target coverage while improving sparing of adjacent organs compared with conventional SABR, first author Elena Moreno-Olmedo and colleagues contend.

A safer treatment option

The team conducted a study to assess the incidence of SABR-related toxicities in patients with histologically confirmed NSCLC undergoing SMART-based SABR. The study included 11 patients with 18 ultracentral lesions, the majority of whom had oligometastatic or olioprogressive disease.

Patients received five to eight treatment fractions, to a median dose of 40 Gy (ranging from 30 to 60 Gy). The researchers generated fixed-field SABR plans with dosimetric aims including a PTV V_100% (the volume receiving at least 100% of the prescription dose) of 95% or above, a PTV V_95% of 98% or above and a maximum dose of between110% and 140%. PTV coverage was compromised where necessary to meet OAR constraints, with a minimum PTV V_100% of at least 70%.

SABR was performed using a 6 MV 0.35 T MRIdian linac with gated delivery during repeated breath-holds, under continuous MR guidance. Based on daily MRI scans, online plan adaptation was performed for all of the 78 delivered fractions.

The researchers report that both the PTV volume and PTV overlap with ultracentral OARs were reduced in SMART treatments compared with conventional SABR. The median SMART PTV was 10.1 cc, compared with 30.4 cc for the simulated SABR PTV, while the median PTV overlap with OARs was 0.85 cc for SMART (8.4% of the PTV) and 4.7 cc for conventional SABR.

In terms of treatment-related side effects for SMART, the rates of acute and late grade 1–2 toxicities were 54% and 18%, respectively, with no grade 3–5 toxicities observed. This demonstrates the technique’s increased safety compared with non-adaptive SABR treatments, which have exhibited severe rates of toxicity, including treatment-related deaths, in ultracentral tumours.

Two-thirds of patients were alive at the median follow-up point of 28 months, and 93% were free from local progression at 12 months. The median progression-free survival was 5.8 months and median overall survival was 20 months.

Acknowledging the short follow-up time frame, the researchers note that additional late toxicities may occur. However, they are hopeful that SMART will be considered as a favourable treatment option for patients with ultracentral NSCLC lesions.

“Our analysis demonstrates that hypofractionated SMART with daily online adaptation for ultracentral NSCLC achieved comparable local control to conventional non-adaptive SABR, with a safer toxicity profile,” they write. “These findings support the consideration of SMART as a safer and effective treatment option for this challenging subgroup of thoracic tumours.”

The post A SMART approach to treating lung cancers in challenging locations appeared first on Physics World.

Researchers in the United Arab Emirates have designed a new catheter that can deliver drugs to entire regions of the brain. Developed by Batoul Khlaifat and colleagues at New York University Abu Dhabi, the catheter’s helical structure and multiple outflow ports could make it both safer and more effective for treating a wide range of neurological disorders.

Modern treatments for brain-related conditions including Parkinson’s disease, epilepsy, and tumours often involve implanting microfluidic catheters that deliver controlled doses of drug-infused fluids to highly localized regions of the brain. Today, these implants are made from highly flexible materials that closely mimic the soft tissue of the brain. This makes them far less invasive than previous designs.

However, there is still much room for improvement, as Khlaifat explains. “Catheter design and function have long been limited by the neuroinflammatory response after implantation, as well as the unequal drug distribution across the catheter’s outlets,” she says.

A key challenge with this approach is that each of the brain’s distinct regions has highly irregular shapes, which makes it incredibly difficult to target via single drug doses. Instead, doses must be delivered either through repeated insertions from a single port at the end of a catheter, or through single insertions across multiple co-implanted catheters. Either way, the approach is highly invasive, and runs the risk of further trauma to the brain.

Multiple ports

In their study, Khlaifat’s team explored how many of these problems stem from existing catheter designs. They tend to be simple tubes with single input and output ports at either end. Using fluid dynamics simulations, they started by investigating how drug outflow would change when multiple output ports are positioned along the length of the catheter.

To ensure this outflow is delivered evenly, they carefully adjusted the diameter of each port to account for the change in fluid pressure along the catheter’s length – so that four evenly spaced ports could each deliver roughly one quarter of the total flow. Building on this innovation, the researchers then explored how the shape of the catheter itself could be adjusted to optimize delivery even further.

“We varied the catheter design from a straight catheter to a helix of the same small diameter, allowing for a larger area of drug distribution in the target implantation region with minimal invasiveness,” explains team member Khalil Ramadi. “This helical shape also allows us to resist buckling on insertion, which is a major problem for miniaturized straight catheters.”

Helical catheter

Based on their simulations, the team fabricated a helical catheter the call Strategic Precision Infusion for Regional Administration of Liquid, or SPIRAL. In their first set of experiments, they tested their simulations in controlled lab conditions. They verified their prediction of even outflow rates across the catheter’s outlets.

“Our helical device was also tested in mouse models alongside its straight counterpart to study its neuroinflammatory response,” Khlaifat says. “There were no significant differences between the two designs.”

Having validated the safety of their approach, the researchers are now hopeful that SPIRAL could pave the way for new and improved methods for targeted drug delivery within the brain. With the ability to target entire regions of the brain with smaller, more controlled doses, this future generation of implanted catheters could ultimately prove to be both safer and more effective than existing designs.

“These catheters could be optimized for each patient through our computational framework to ensure only regions that require dosing are exposed to therapy, all through a single insertion point in the skull,” describes team member Mahmoud Elbeh. “This tailored approach could improve therapies for brain disorders such as epilepsy and glioblastomas.”

The research is described in the Journal of Neural Engineering.

The post Spiral catheter optimizes drug delivery to the brain appeared first on Physics World.

From quantum utility today to quantum advantage tomorrow: incumbent technology companies – among them Google, Amazon, IBM and Microsoft – and a wave of ambitious start-ups are on a mission to transform quantum computing from applied research endeavour to mainstream commercial opportunity. The end-game: quantum computers that can be deployed at-scale to perform computations significantly faster than classical machines while addressing scientific, industrial and commercial problems beyond the reach of today’s high-performance computing systems.

Meanwhile, as technology translation gathers pace across the quantum supply chain, government laboratories and academic scientists must maintain their focus on the “hard yards” of precompetitive research. That means prioritizing foundational quantum hardware and software technologies, underpinned by theoretical understanding, experimental systems, device design and fabrication – and pushing out along all these R&D pathways simultaneously.

Bringing order to disorder

Equally important is the requirement to understand and quantify the relative performance of quantum computers from different manufacturers as well as across the myriad platform technologies – among them superconducting circuits, trapped ions, neutral atoms as well as photonic and semiconductor processors. A case study in this regard is a broad-scope UK research collaboration that, for the past four years, has been reviewing, collecting and organizing a holistic taxonomy of metrics and benchmarks to evaluate the performance of quantum computers against their classical counterparts as well as the relative performance of competing quantum platforms.

Funded by the National Quantum Computing Centre (NQCC), which is part of the UK National Quantum Technologies Programme (NQTP), and led by scientists at the National Physical Laboratory (NPL), the UK’s National Metrology Institute, the cross-disciplinary consortium has taken on an endeavour that is as sprawling as it is complex. The challenge lies in the diversity of quantum hardware platforms in the mix; also the emergence of two different approaches to quantum computing – one being a gate-based framework for universal quantum computation, the other an analogue approach tailored to outperforming classical computers on specific tasks.

“Given the ambition of this undertaking, we tapped into a deep pool of specialist domain knowledge and expertise provided by university colleagues at Edinburgh, Durham, Warwick and several other centres-of-excellence in quantum,” explains Ivan Rungger, a principal scientist at NPL, professor in computer science at Royal Holloway, University of London, and lead scientist on the quantum benchmarking project. That core group consulted widely within the research community and with quantum technology companies across the nascent supply chain. “The resulting study,” adds Rungger, “positions transparent and objective benchmarking as a critical enabler for trust, comparability and commercial adoption of quantum technologies, aligning closely with NPL’s mission in quantum metrology and standards.”

Not all metrics are equal – or mature

For context, a number of performance metrics used to benchmark classical computers can also be applied directly to quantum computers, such as the speed of operations, the number of processing units, as well as the probability of errors to occur in the computation. That only goes so far, though, with all manner of dedicated metrics emerging in the past decade to benchmark the performance of quantum computers – ranging from their individual hardware components to entire applications.

Complexity reigns, it seems, and navigating the extensive literature can prove overwhelming, while the levels of maturity for different metrics varies significantly. Objective comparisons aren’t straightforward either – not least because variations of the same metric are commonly deployed; also the data disclosed together with a reported metric value is often not sufficient to reproduce the results.

“Many of the approaches provide similar overall qualitative performance values,” Rungger notes, “but the divergence in the technical implementation makes quantitative comparisons difficult and, by extension, slows progress of the field towards quantum advantage.”

The task then is to rationalize the metrics used to evaluate the performance for a given quantum hardware platform to a minimal yet representative set agreed across manufacturers, algorithm developers and end-users. These benchmarks also need to follow some agreed common approaches to fairly and objectively evaluate quantum computers from different equipment vendors.

With these objectives in mind, Rungger and colleagues conducted a deep-dive review that has yielded a comprehensive collection of metrics and benchmarks to allow holistic comparisons of quantum computers, assessing the quality of hardware components all the way to system-level performance and application-level metrics.

Drill down further and there’s a consistent format for each metric that includes its definition, a description of the methodology, the main assumptions and limitations, and a linked open-source software package implementing the methodology. The software transparently demonstrates the methodology and can also be used in practical, reproducible evaluations of all metrics.

“As research on metrics and benchmarks progresses, our collection of metrics and the associated software for performance evaluation are expected to evolve,” says Rungger. “Ultimately, the repository we have put together will provide a ‘living’ online resource, updated at regular intervals to account for community-driven developments in the field.”

From benchmarking to standards

Innovation being what it is, those developments are well under way. For starters, the importance of objective and relevant performance benchmarks for quantum computers has led several international standards bodies to initiate work on specific areas that are ready for standardization – work that, in turn, will give manufacturers, end-users and investors an informed evaluation of the performance of a range of quantum computing components, subsystems and full-stack platforms.

What’s evident is that the UK’s voice on metrics and benchmarking is already informing the collective conversation around standards development. “The quantum computing community and international standardization bodies are adopting a number of concepts from our approach to benchmarking standards,” notes Deep Lall, a quantum scientist in Rungger’s team at NPL and lead author of the study. “I was invited to present our work to a number of international standardization meetings and scientific workshops, opening up widespread international engagement with our research and discussions with colleagues across the benchmarking community.”

He continues: “We want the UK effort on benchmarking and metrics to shape the broader international effort. The hope is that the collection of metrics we have pulled together, along with the associated open-source software provided to evaluate them, will guide the development of standardized benchmarks for quantum computers and speed up the progress of the field towards practical quantum advantage.”

That’s a view echoed – and amplified – by Cyrus Larijani, NPL’s head of quantum programme. “As we move into the next phase of NPL’s quantum strategy, the importance of evidence-based decision making becomes ever-more critical,” he concludes. “By grounding our strategic choices in robust measurement science and real-world data, we ensure that our innovations not only push the boundaries of quantum technology but also deliver meaningful impact across industry and society.”

Further reading

Deep Lall et al. 2025 A  review and collection of metrics and benchmarks for quantum computers: definitions, methodologies and software https://arxiv.org/abs/2502.06717

End note: NPL retains copyright on this article.

The post Performance metrics and benchmarks point the way to practical quantum advantage appeared first on Physics World.

This episode of the Physics World Weekly podcast explores how quantum computing and artificial intelligence can be combined to help physicists search for rare interactions in data from an upgraded Large Hadron Collider.

My guest is Javier Toledo-Marín, and we spoke at the Perimeter Institute in Waterloo, Canada. As well as having an appointment at Perimeter, Toledo-Marín is also associated with the TRIUMF accelerator centre in Vancouver.

Toledo-Marín and colleagues have recently published a paper called “Conditioned quantum-assisted deep generative surrogate for particle–calorimeter interactions”.

The post Quantum computing and AI join forces for particle physics appeared first on Physics World.

The microelectronics sector is known for its relentless drive for innovation, continually delivering performance and efficiency gains within ever more compact form factors. Anyone aspiring to build a career in this fast-moving field needs not just a thorough grounding in current tools and techniques, but also an understanding of the next-generation materials and structures that will propel future progress.

That’s the premise behind a Master’s programme in microelectronics technology and materials at the Hong Kong Polytechnic University (PolyU). Delivered by the Department for Applied Physics, globally recognized for its pioneering research in technologies such as two-dimensional materials, nanoelectronics and artificial intelligence, the aim is to provide students with both the fundamental knowledge and practical skills they need to kickstart their professional future – whether they choose to pursue further research or to find a job in industry.

“The programme provides students with all the key skills they need to work in microelectronics, such as circuit design, materials processing and failure analysis,” says programme leader Professor Zhao Jiong, who research focuses on 2D ferroelectrics. “But they also have direct access to more than 20 faculty members who are actively investigating novel materials and structures that go beyond silicon-based technologies.”

The course in also unusual in providing a combined focus on electronics engineering and materials science, providing students with a thorough understanding of the underlying semiconductors and device structures as well as their use in mass-produced integrated circuits. That fundamental knowledge is reinforced through regular experimental work, providing the students with hands-on experience of fabricating and testing electronic devices. “Our cleanroom laboratory is equipped with many different instruments for microfabrication, including thin-film deposition, etching and photolithography, as well as advanced characterization tools for understanding their operating mechanisms and evaluating their performance,” adds Zhao.

In a module focusing on thin-film materials, for example, students gain valuable experience from practical sessions that enable them to operate the equipment for different growth techniques, such as sputtering, molecular beam epitaxy, and both physical and chemical vapour deposition. In another module on materials analysis and characterization, the students are tasked with analysing the layered structure of a standard computer chip by making cross-sections that can be studied with a scanning electron microscope.

That practical experience extends to circuit design, with students learning how to use state-of-the-art software tools for configuring, simulating and analysing complex electronic layouts. “Through this experimental work students gain the technical skills they need to design and fabricate integrated circuits, and to optimize their performance and reliability through techniques like failure analysis,” says Professor Dai Jiyan, PolyU Associate Dean of Students, who also teaches the module on thin-film materials. “This hands-on experience helps to prepare them for working in a manufacturing facility or for continuing their studies at the PhD level.”

Also integrated into the teaching programme is the use of artificial intelligence to assist key tasks, such as defect analysis, materials selection and image processing. Indeed, PolyU has established a joint laboratory with Huawei to investigate possible applications of AI tools in electronic design, providing the students with early exposure to emerging computational methods that are likely to shape the future of the microelectronics industry. “One of our key characteristics is that we embed AI into our teaching and laboratory work,” says Dai. “Two of the modules are directly related to AI, while the joint lab with Huawei helps students to experiment with using AI in circuit design.”

Now in its third year, the Master’s programme was designed in collaboration with Hong Kong’s Applied Science and Technology Research Institute (ASTRI), established in 2000 to enhance the competitiveness of the region through the use of advanced technologies. Researchers at PolyU already pursue joint projects with ASTRI in areas like chip design, microfabrication and failure analysis. As part of the programme, these collaborators are often invited to give guest lectures or to guide the laboratory work. “Sometimes they even provide some specialized instruments for the students to use in their experiments,” says Zhao. “We really benefit from this collaboration.”

Once primed with the knowledge and experience from the taught modules, the students have the opportunity to work alongside one of the faculty members on a short research project. They can choose whether to focus on a topic that is relevant to present-day manufacturing, such as materials processing or advanced packaging technologies, or to explore the potential of emerging materials and devices across applications ranging from solar cells and microfluidics to next-generation memories and neuromorphic computing.

“It’s very interesting for the students to get involved in these projects,” says Zhao. “They learn more about the research process, which can make them more confident to take their studies to the next level. All of our faculty members are engaged in important work, and we can guide the students towards a future research field if that’s what they are interested in.”

There are also plenty of progression opportunities for those who are more interested in pursuing a career in industry. As well as providing support and advice through its joint lab in AI, Huawei arranges visits to its manufacturing facilities and offers some internships to interested students. PolyU also organizes visits to Hong Kong’s Science Park, home to multinational companies such as Infineon as well as a large number of start-up companies in the microelectronics sector. Some of these might support a student’s research project, or offer an internship in areas such as circuit design or microfabrication.

The international outlook offered by PolyU has made the Master’s programme particularly appealing to students from mainland China, but Zhao and Dai believe that the forward-looking ethos of the course should make it an appealing option for graduates across Asia and beyond. “Through the programme, the students gain knowledge about all aspects of the microelectronics industry, and how it is likely to evolve in the future,” says Dai. “The knowledge and technical skills gained by the students offer them a competitive edge for building their future career, whether they want to find a job in industry or to continue their research studies.”

The post Master’s programme takes microelectronics in new directions appeared first on Physics World.

Pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, is an aggressive tumour with a poor prognosis. Surgery remains the only potential cure, but is feasible in just 10–15% of cases. A team headed up at Sichuan University in China has now developed a selective laser ablation technique designed to target PDAC while leaving healthy pancreatic tissue intact.

Thermal ablation techniques, such as radiofrequency, microwave or laser ablation, could provide a treatment option for patients with locally advanced PDAC, but existing methods risk damaging surrounding blood vessels and healthy pancreatic tissues. The new approach, described in Optica, uses the molecular fingerprint of pancreatic tumours to enable selective ablation.

The technique exploits the fact that PDAC tissue contains a large amount of collagen compared with healthy pancreatic tissue. Amide-I collagen fibres exhibit a strong absorption peak at 6.1 µm, thus the researchers surmised that tuning the treatment laser to this resonant wavelength could enable efficient tumour ablation with minimal collateral thermal damage. As such, they designed a femtosecond pulsed laser that can deliver 6.1 µm pulses with a power of more than 1 W.

“We developed a mid-infrared femtosecond laser system for the selective tissue ablation experiment,” says team leader Houkun Liang. “The system is tunable in the wavelength range of 5 to 11 µm, aligning with various molecular fingerprint absorption peaks such as amide proteins, cholesteryl ester, hydroxyapatite and so on.”

Liang and colleagues first examined the ablation efficiency of three different laser wavelengths on two types of pancreatic cancer cells. Compared with non-resonant wavelengths of 1 and 3 µm, the collagen-resonant 6.1 µm laser was far more effective in killing pancreatic cancer cells, reducing cell viability to ranges of 0.27–0.32 and 0.37–0.38, at 0 and 24 h, respectively.

The team observed similar results in experiments on ectopic PDAC tumours cultured on the backs of mice. Irradiation at 6.1 µm led to five to 10 times deeper tumour ablation than seen for the non-resonant wavelengths (despite using a laser power of 5 W for 1 µm ablation and just 500 mW for 6.1 and 3 µm), indicating that 6.1 µm is the optimal wavelength for PDAC ablation surgery.

To validate the feasibility and safety of 6.1 µm laser irradiation, the team used the technique to treat PDAC tumours on live mice. Nine days after ablation, the tumour growth rate in treated mice was significantly suppressed, with an average tumour volume of 35.3 mm³. In contrast, tumour volume in a control group of untreated mice reached an average of 292.7 mm³, roughly eight times the size of the ablated tumours. No adverse symptoms were observed following the treatment.

Clinical potential

The researchers also used 6.1 µm laser irradiation to ablate pancreatic tissue samples (including normal tissue and PDAC) from 13 patients undergoing surgical resection. They used a laser power of 1 W and four scanning speeds (0.5, 1, 2 and 3 mm/s) with 10 ablation passes, examining 20 to 40 samples for each parameter.

At the slower scanning speeds, excessive energy accumulation resulted in comparable ablation depths. At speeds of 2 or 3 mm/s, however, the average ablation depths in PDAC samples were 2.30 and 2.57 times greater than in normal pancreatic tissue, respectively, demonstrating the sought-after selective ablation. At 3 mm/s, for example, the ablation depth in tumour was 1659.09±405.97 µm, compared with 702.5±298.32 µm in normal pancreas.

The findings show that by carefully controlling the laser power, scanning speed and number of passes, near-complete ablation of PDACs can be achieved, with minimal damage to surrounding healthy tissues.

To further investigate the clinical potential of this technique, the researchers developed an anti-resonant hollow-core fibre (AR-HCF) that can deliver high-power 6.1 µm laser pulses deep inside the human body. The fibre has a core diameter of approximately 113 µm and low bending losses at radii under 10 cm. The researchers used the AR-HCF to perform 6.1 µm laser ablation of PDAC and normal pancreas samples. The ablation depth in PDAC was greater than in normal pancreas, confirming the selective ablation properties.

“We are working together with a company to make a medical-grade fibre system to deliver the mid-infrared femtosecond laser. It consists of AR-HCF to transmit mid-infrared femtosecond pulses, a puncture needle and a fibre lens to focus the light and prevent liquid tissue getting into the fibre,” explains Liang. “We are also making efforts to integrate an imaging unit into the fibre delivery system, which will enable real-time monitoring and precise surgical guidance.”

Next, the researchers aim to further optimize the laser parameters and delivery systems to improve ablation efficiency and stability. They also plan to explore the applicability of selective laser ablation to other tumour types with distinct molecular signatures, and to conduct larger-scale animal studies to verify long-term safety and therapeutic outcomes.

“Before this technology can be used for clinical applications, highly comprehensive biological safety assessments are necessary,” Liang emphasizes. “Designing well-structured clinical trials to assess efficacy and risks, as well as navigating regulatory and ethical approvals, will be critical steps toward translation. There is a long way to go.”

The post Resonant laser ablation selectively destroys pancreatic tumours appeared first on Physics World.

Low-energy electrons escape from some materials via distinct “doorway” states, according to a study done by physicists at Austria’s Vienna Institute of Technology. The team studied graphene-based materials and found that the nature of the doorway states depended on the number of graphene layers in the sample.

Low-energy electron (LEE) emission from solids is used across a range of materials analysis and processing applications including scanning electron microscopy and electron-beam induced deposition. However, the precise physics of the emission process is not well understood.

Electrons are ejected from a material when a beam of electrons is fired at its surface. Some of these incident electrons will impart energy to electrons residing in the material, causing some resident electrons to be emitted from the surface. In the simplest model, the minimum energy needed for this LEE emission is the electron binding energy of the material.

Frog in a box

In this new study, however, researchers have shown that exceeding the binding energy is not enough for LEE emission from graphene-based materials. Not only does the electron need this minimum energy, it must also be in a specific doorway state or it is unlikely to escape. The team compare this phenomenon to the predicament of a frog in a cardboard box with a window. Not only must the frog hop a certain height to escape the box, it must also begin its hop from a position that will result in it travelling through the hole (see figure).

For most materials, the energy spectrum of LEE electrons is featureless. However, it was known that graphite’s spectrum has an “X state” at about 3.3 eV, where emission is enhanced. This state could be related to doorway states.

To search for doorway states, the Vienna team studied LEE emission from graphite as well as from single-layer and bi-layer graphene. Graphene is a sheet of carbon just one atom thick. Sheets can stick together via the relatively weak Van der Waals force to create multilayer graphene – and ultimately graphite, which comprises a large number of layers.

Because electrons are mostly confined within the graphene layers, the electronic states of single-layer, bi-layer and multi-layer graphene are broadly similar. As a result, it was expected that these materials would have similar LEE emission spectra . However, the Vienna team found a surprising difference.

Emission and reflection

The team made their discovery by firing a beam of relatively low energy electrons (173 eV) incident at 60° to the surface of single-layer and bi-layer graphene as well as graphite. The scattered electrons are then detected at the same angle of reflection. Meanwhile, a second detector is pointed normal to the surface to capture any emitted electrons. In quantum mechanics electrons are indistinguishable, so the modifiers scattered and emitted are illustrative, rather than precise.

The team looked for coincident signals in both detectors and plotted their results as a function of energy in 2D “heat maps”. These plots revealed that bi-layer graphene and graphite each had doorway states – but at different energies. However, single-layer graphene did not appear to have any doorway states. By combining experiments with calculations, the team showed that doorway states emerge above a certain number of layers. As a result the researchers showed that graphite’s X state can be attributed in part to a doorway state that appears at about five layers of graphene.

“For the first time, we’ve shown that the shape of the electron spectrum depends not only on the material itself, but crucially on whether and where such resonant doorway states exist,” explains Anna Niggas at the Vienna Institute of Technology.

As well as providing important insights in how the electronic properties of graphene morph into the properties of graphite, the team says that their research could also shed light on the properties of other layered materials.

The research is described in Physical Review Letters.

The post Doorway states spotted in graphene-based materials appeared first on Physics World.

NASA’s Jet Propulsion Laboratory (JPL) is to lay off some 550 employees as part of a restructuring that began in July. The action affects about 11% of JPL’s employees and represents the lab’s third downsizing in the past 20 months. When the layoffs are complete by the end of the year, the lab will have roughly 4500 employees, down from about 6500 at the start of 2024. A further 4000 employees have already left NASA during the past six months via sacking, retirement or voluntary buyouts.

Managed by the California Institute of Technology in Pasadena, JPL oversees scientific missions such as the Psyche asteroid probe, the Europa Clipper and the Perseverance rover on Mars. The lab also operates the Deep Space Network that keeps Earth in communication with unmanned space missions. JPL bosses already laid off about 530 staff – and 140 contractors – in February last year followed by another 325 people in November 2024.

JPL director Dave Gallagher insists, however, that the new layoffs are not related to the current US government shutdown that began on 1 October. “[They are] essential to securing JPL’s future by creating a leaner infrastructure, focusing on our core technical capabilities, maintaining fiscal discipline, and positioning us to compete in the evolving space ecosystem,” he says in a message to employees.

Judy Chu, Democratic Congresswoman for the constituency that includes JPL, is less optimistic. “Every layoff devastates the highly skilled and uniquely talented workforce that has made these accomplishments possible,” she says. “Together with last year’s layoffs, this will result in an untold loss of scientific knowledge and expertise that threatens the very future of American leadership in space exploration and scientific discovery.”

John Logsdon, professor emeritus at George Washington University and founder of the university’s Space Policy Institute, says that the cuts are a direct result of the Trump administration’s approach to science and technology. “The administration gives low priority to robotic science and exploration, and has made draconic cuts to the science budget; that budget supports JPL’s work,” he told Physics World. “With these cuts, there is not enough money to support a JPL workforce sized for more ambitious activities. Ergo, staff cuts.”

The post NASA’s Jet Propulsion Lab lays off a further 10% of staff appeared first on Physics World.