When implanted medical devices like urinary stents and catheters get clogged with biofilms, the usual solution is to take them out and replace them with new ones. Now, however, researchers at the University of Bern and ETH Zurich, Switzerland have developed an alternative. By incorporating ultrasound-activated moving structures into their prototype “stent-on-a-chip” device, they showed it is possible to remove biofilms without removing the device itself. If translated into clinical practice, the technology could increase the safe lifespan of implants, saving money and avoiding operations that are uncomfortable and sometimes hazardous for patients.

Biofilms are communities of bacterial cells that adhere to natural surfaces in the body as well as artificial structures such as catheters, stents and other implants. Because they are encapsulated by a protective, self-produced extracellular matrix made from polymeric substances, they are mechanically robust and resistant to standard antibacterial measures. If not removed, they can cause infections, obstructions and other complications.

Intense, steady flows push away impurities

The new technology, which was co-developed by Cornel Dillinger, Pedro Amado and other members of Francesco Clavica and Daniel Ahmed’s research teams, takes advantage of recent advances in the fields of robotics and microfluidics. Its main feature is a coating made from microscopic hair-like structures known as cilia. Under the influence of an acoustic field, which is applied externally via a piezoelectric transducer, these cilia begin to move. This movement produces intense, steady fluid flows with velocities of up to 10 mm/s – enough to break apart encrusted deposits (made from calcium carbonate, for example) and flush away biofilms from the inner and outer surfaces of implanted urological devices.

“This is a major advance compared to existing stents and catheters, which require regular replacements to avoid obstruction and infections,” Clavica says.

The technology is also an improvement on previous efforts to clear implants by mechanical means, Ahmed adds. “Our polymeric cilia in fact amplify the effects of ultrasound by allowing for an effect known as acoustic streaming at frequencies of 20 to 100 kHz,” he explains. “This frequency is lower than that possible with previous microresonator devices developed to work in a similar way that had to operate in the MHz-frequency range.”

The lower frequency achieves the desired therapeutic effects while prioritizing patient safety and minimizing the risk of tissue damage, he adds.

Wider applications

In creating their technology, the researchers were inspired by biological cilia, which are a natural feature of physiological systems such as the reproductive and respiratory tracts and the central nervous system. Future versions, they say, could apply the ultrasound probe directly to a patient’s skin, much as handheld probes of ultrasound scanners are currently used for imaging. “This technology has potential applications beyond urology, including fields like visceral surgery and veterinary medicine, where keeping implanted medical devices clean is also essential,” Clavica says.

The researchers now plan to test new coatings that would reduce contact reactions (such as inflammation) in the body. They will also explore ways of improving the device’s responsiveness to ultrasound – for example by depositing thin metal layers. “These modifications could not only improve acoustic streaming performance but could also provide additional antibacterial benefits,” Clavica tells Physics World.

In the longer term, the team hope to translate their technology into clinical applications. Initial tests that used a custom-built ultrasonic probe coupled to artificial tissue have already demonstrated promising results in generating cilia-induced acoustic streaming, Clavica notes. “In vivo animal studies will then be critical to validate safety and efficacy prior to clinical adoption,” he says.

The present study is detailed in PNAS.

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DoD increases contract ceiling to $1.3 billion as artificial intelligence transforms battlefield targeting

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Cyril Hilsum, a former president of the Institute of Physics (IOP), celebrated his 100th birthday last week at a special event held at the Royal Society of Chemistry.

Born on 17 May 1925, Hilsum completed a degree in physics at University College London in 1945. During his career he worked at the Services Electronics Research Laboratory and the Royal Radar Establishment and in 1983 was appointed chief scientist of GEC Hirst Research Centre, where he later became research director before retiring aged 70.

Hilsum helped develop commercial applications for the semiconductor gallium arsenide and is responsible for creating the UK’s first semiconductor laser as well as developments that led to modern liquid crystal display technologies.

Between 1988 and 1990 he was president of the IOP, which publishes Physics World, and in 1990 was appointed a Commander of the Order of the British Empire (CBE) for “services to the Electrical and Electronics Industry”.

Hilsum was honoured by many prizes during his career including IOP awards such as the Max Born Prize in 1987, the Faraday Medal in 1988 as well as the Richard Glazebrook Medal and Prize in 1998. In 2007 he was awarded the Royal Society’s Royal Medal ‘for his many outstanding contributions and for continuing to use his prodigious talents on behalf of industry, government and academe to this day’.

Despite now being a centenarian, Hilsum still works part-time as chief science officer for Infi-tex Ltd, which produces force sensors for use in textiles.

“My birthday event was an amazing opportunity for me to greet old colleagues and friends,” Hilsum told Physics World. “Many had not seen each other since they had worked together in the distant past. It gave me a rare opportunity to acknowledge the immense contributions they had made to my career.”

Hilsum says that while the IOP gives much support to applied physics, there is still a great need for physicists “to give critical contributions to the lives of society as a whole”.

“As scientists, we may welcome progress in the subject, but all can get pleasure in seeing the results in their home, on their iPhone, or especially in their hospital!” he adds.

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The European Space Agency will request funding from member states for an Earth observation satellite system for security applications, blurring the line between its traditional civil focus and defense work.

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Learn why more people are choosing dogs over having children and what this says about modern families.

Californian software startup PiLogic announced $4 million in seed funding May 22 to develop satellite diagnostics and other artificial intelligence tools tailored for space applications.

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Learn how these tiny clownfish, famous for their role in the “Finding Nemo” films, survive the trouble of heatwaves.

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Blue Origin revealed new details about its development of an Artemis lunar lander as the company nears the first launch of a smaller lander.

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ST. LOUIS — The National Geospatial-Intelligence Agency announced awards May 21 to Palantir Technologies, the University of Illinois and Ursa Space Systems at the GEOINT Symposium 2025. Through a $13.8 […]

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Learn how dishwashers release microplastics and nanoplastics that pose environmental risks through polluted wastewater.

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The Enhanced Games, where athletes are allowed to take performance-enhancing drugs, will host its first event in May. One “enhanced” former Olympic swimmer has already broken the 50-meter freestyle record.

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This sparkling solution can aid conservationists as they track at-risk water voles in their natural habitat.

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ST. LOUIS – Artificial intelligence combined with human insight promises to transform geospatial intelligence, experts said at the GEOINT Symposium 2025. But it will require standards, data verification and monitoring […]

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Scientists have created a novel antimicrobial coating that, when mixed with paint, can be applied to a range of surfaces to destroy bacteria and viruses – including particularly persistent and difficult to kill strains like MRSA, flu virus and SARS-CoV-2. The development potentially paves the way for substantial improvements in scientific, commercial and clinical hygiene.

The University of Nottingham-led team made the material by combining chlorhexidine digluconate (CHX) – a disinfectant commonly used by dentists to treat mouth infections and by clinicians for cleaning before surgery – with everyday paint-on epoxy resin. Using this material, the team worked with staff at Birmingham-based specialist coating company Indestructible Paint to create a prototype antimicrobial paint. They found that, when dried, the coating can kill a wide range of pathogens.

The findings of the study, which was funded by the Royal Academy of Engineering Industrial Fellowship Scheme, were published in Scientific Reports.

Persistent antimicrobial protection

As part of the project, the researchers painted the antimicrobial coating onto a surface and used a range of scientific techniques to analyse the distribution of the biocide in the paint, to confirm that it remained uniformly distributed at a molecular level.

According to project leader Felicity de Cogan, the new paint can be used to provide antimicrobial protection on a wide array of plastic and hard non-porous surfaces. Crucially, it could be effective in a range of clinical environments, where surfaces like hospital beds and toilet seats can act as a breeding ground for bacteria for extended periods of time – even after the introduction of stringent cleaning regimes.

The team, based at the University’s School of Pharmacy, is also investigating the material’s use in the transport and aerospace industries, especially on frequently touched surfaces in public spaces such as aeroplane seats and tray tables.

“The antimicrobial in the paint is chlorhexidine – a biocide commonly used in products like mouthwash. Once it is added, the paint works in exactly the same way as all other paint and the addition of the antimicrobial doesn’t affect its application or durability on the surface,” says de Cogan.

The researchers also note that adding CHX to the epoxy resin did not affect its optical transparency.

According to de Cogan, the novel concoction has a range of potential scientific, clinical and commercial applications.

“We have shown that it is highly effective against a range of different pathogens like E. coli and MRSA. We have also shown that it is effective against bacteria even when they are already resistant to antibiotics and biocides,” she says. “This means the technology could be a useful tool to circumvent the global problem of antimicrobial resistance.”

In de Cogan’s view, there are also number of major advantages to using the new coating to tackle bacterial infection – especially when compared to existing approaches – further boosting the prospects of future applications.

The key advantage of the technology is that the paint is “self-cleaning” – meaning that it would no longer be necessary to carry out the arduous task of repeatedly cleaning a surface to remove harmful microbes. Instead, after a single application, the simple presence of the paint on the surface would actively and continuously kill bacteria and viruses whenever they come into contact with it.

“This means that you can be sure a surface won’t pass on infections when you touch it,” says de Cogan.

“We are looking at more extensive testing in harsher environments and long-term durability testing over months and years. This work is ongoing and we will be following up with another publication shortly,” she adds.

The post Bacteria-killing paint could dramatically improve hospital hygiene appeared first on Physics World.

A tiny but crucial agency that maintains physical coordinates like latitude and longitude in the US is struggling as the Trump administration forces out federal employees.

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Constellations aim to bridge gap between space-based monitoring and ground-level firefighting efforts

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Peer review is a cornerstone of academic publishing. It is how we ensure that published science is valid. Peer review, by which researchers judge the quality of papers submitted to journals, stops pseudoscience from being peddled as equivalent to rigorous research. At the same time, the peer-review system is under considerable strain as the number of journal articles published each year increases, jumping from 1.9 million in 2016 to 2.8 million in 2022, according to Scopus and Web of Science.

All these articles require experienced peer reviewers, with papers typically taking months to go through peer review. This cannot be blamed alone on the time taken to post manuscripts and reviews back and forth between editors and reviewers, but instead is a result of high workloads and, fundamentally, how busy everyone is. Given peer reviewers need to be expert in their field, the pool of potential reviewers is inherently limited. A bottleneck is emerging as the number of papers grows quicker than the number of researchers in academia.

Scientific publishers have long been central to managing the process of peer review. For anyone outside academia, the concept of peer review may seem illogical given that researchers spend their time on it without much acknowledgement. While initiatives are in place to change this such as outstanding-reviewer awards and the Web of Science recording reviewer data, there is no promise that such recognition will be considered when looking for permanent positions or applying for promotion.

The impact of open access

Why, then, do we agree to review? As an active researcher myself in quantum physics, I peer-reviewed more than 40 papers last year and I’ve always viewed it as a duty. It’s a necessary time-sink to make our academic system function, to ensure that published research is valid and to challenge questionable claims. However, like anything people do out of a sense of duty, inevitably there are those who will seek to exploit it for profit.

Many journals today are open access, in which fees, known as article-processing charges, are levied to make the published work freely available online. It makes sense that costs need to be imposed – staff working at publishing companies need paying; articles need editing and typesetting; servers need be maintained and web-hosting fees have to be paid. Recently, publishers have invested heavily in digital technology and developed new ways to disseminate research to a wider audience.

Open access, however, has encouraged some publishers to boost revenues by simply publishing as many papers as possible. At the same time, there has been an increase in retractions, especially of fabricated or manipulated manuscripts sold by “paper mills”. The rise of retractions isn’t directly linked to the emergence of open access, but it’s not a good sign, especially when the academic publishing industry reports profit margins of roughly 40% – higher than many other industries. Elsevier, for instance, publishes nearly 3000 journals and in 2023 its parent company, Relx, recorded a profit of £1.79bn. This is all money that was either paid in open-access fees or by libraries (or private users) for journal subscriptions but ends up going to shareholders rather than science.

It’s important to add that not all academic publishers are for-profit. Some, like the American Physical Society (APS), IOP Publishing, Optica, AIP Publishing and the American Association for the Advancement of Science – as well as university presses – are wings of academic societies and universities. Any profit they make is reinvested into research, education or the academic community. Indeed, IOP Publishing, AIP Publishing and the APS have formed a new “purpose-led publishing” coalition, in which the three publishers confirm that they will continue to reinvest the funds generated from publishing back into research and “never” have shareholders that result in putting “profit above purpose”.

But many of the largest publishers – the likes of Springer Nature, Elsevier, Taylor and Francis, MDPI and Wiley – are for-profit companies and are making massive sums for their shareholders. Should we just accept that this is how the system is? If not, what can we do about it and what impact can we as individuals have on a multi-billion-dollar industry? I have decided that I will no longer review for, nor submit my articles (when corresponding author) to, any for-profit publishers.

I’m lucky in my field that I have many good alternatives such as the arXiv overlay journal Quantum, IOP Publishing’s Quantum Science and Technology, APS’s Physical Review X Quantum and Optica Quantum. If your field doesn’t, then why not push for them to be created? We may not be able to dismantle the entire for-profit publishing industry, but we can stop contributing to it (especially those who have a permanent job in academia and are not as tied down by the need to publish in high impact factor journals). Such actions may seem small, but together can have an effect and push to make academia the environment we want to be contributing to. It may sound radical to take change into your own hands, but it’s worth a try. You never know, but it could help more money make its way back into science.

The post Why I stopped submitting my work to for-profit publishers appeared first on Physics World.

Researchers from four universities in Shanghai, China, are developing a practical visual assistance system to help blind and partially sighted people navigate. The prototype system combines lightweight camera headgear, rapid-response AI-facilitated software and artificial “skins” worn on the wrists and finger that provide physiological sensing. Functionality testing suggests that the integration of visual, audio and haptic senses can create a wearable navigation system that overcomes current designs’ adoptability and usability concerns.

Worldwide, 43 million people are blind, according to 2021 estimates by the International Agency for the Prevention of Blindness. Millions more are so severely visually impaired that they require the use of a cane to navigate.

Visual assistance systems offer huge potential as navigation tools, but current designs have many drawbacks and challenges for potential users. These include limited functionality with respect to the size and weight of headgear, battery life and charging issues, slow real-time processing speeds, audio command overload, high system latency that can create safety concerns, and extensive and sometimes complex learning requirements.

Innovations in miniaturized computer hardware, battery charge longevity, AI-trained software to decrease latency in auditory commands, and the addition of lightweight wearable sensory augmentation material providing near-real-time haptic feedback are expected to make visual navigation assistance viable.

The team’s prototype visual assistance system, described in Nature Machine Intelligence, incorporates an RGB-D (red, green, blue, depth) camera mounted on a 3D-printed glasses frame, ultrathin artificial skins, a commercial lithium-ion battery, a wireless bone-conducting earphone and a virtual reality training platform interfaced via triboelectric smart insoles. The camera is connected to a microcontroller via USB, enabling all computations to be performed locally without the need for a remote server.

When a user sets a target using a voice command, AI algorithms process the RGB-D data to estimate the target’s orientation and determine an obstacle-free direction in real time. As the user begins to walk to the target, bone conduction earphones deliver spatialized cues to guide them, and the system updates the 3D scene in real time.

The system’s real-time visual recognition incorporates changes in distance and perspective, and can compensate for low ambient light and motion blur. To provide robust obstacle avoidance, it combines a global threshold method with a ground interval approach to accurately detect overhead hanging, ground-level and sunken obstacles, as well as sloping or irregular ground surfaces.

First author Jian Tang of Shanghai Jiao Tong University and colleagues tested three audio feedback approaches: spatialized cues, 3D sounds and verbal instructions. They determined that spatialized cues are the most rapid to convey and be understood and provide precise direction perception.

Real-world testing A visually impaired person navigates through a cluttered conference room. (Courtesy: Tang et al. Nature Machine Intelligence)

To complement the audio feedback, the researchers developed stretchable artificial skin – an integrated sensory-motor device that provides near-distance alerting. The core component is a compact time-of-flight sensor that vibrates to stimulate the skin when the distance to an obstacle or object is smaller than a predefined threshold. The actuator is designed as a slim, lightweight polyethylene terephthalate cantilever. A gap between the driving circuit and the skin promotes air circulation to improve skin comfort, breathability and long-term wearability, as well as facilitating actuator vibration.

Users wear the sensor on the back of an index or middle finger, while the actuator and driving circuit are worn on the wrist. When the artificial skin detects a lateral obstacle, it provides haptic feedback in just 18 ms.

The researchers tested the trained system in virtual and real-world environments, with both humanoid robots and 20 visually impaired individuals who had no prior experience of using visual assistance systems. Testing scenarios included walking to a target while avoiding a variety of obstacles and navigating through a maze. Participants’ navigation speed increased with training and proved comparable to walking with a cane. Users were also able to turn more smoothly and were more efficient at pathfinding when using the navigation system than when using a cane.

“The proficient completion of tasks mirroring real-world challenges underscores the system’s effectiveness in meeting real-life challenges,” the researchers write. “Overall, the system stands as a promising research prototype, setting the stage for the future advancement of wearable visual assistance.”

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New metric identifying “persistently disruptive” papers offers a “bright spot” amid signs of declining innovation

NASA says a “multi-year” budget shortfall even before the cuts in the fiscal year 2026 budget have led it to consider reductions in crew size and research on the ISS.

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The Golden Dome program represents one of the most ambitious missile defense initiatives in U.S. history.

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Learn more about the migrations of East Australian humpback whales, which were traditionally thought to travel from polar to tropical waters to give birth.

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Industry officials: Cuts of this magnitude would be a stunning reversal of policy

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