Medetomidine, a veterinary sedative, mixed into fentanyl has sent thousands to hospitals, not only for overdose but for life-threatening withdrawal. It is spreading to other cities.

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Two men toting long guns opened fire on hundreds of people who were celebrating Hanukkah on Bondi Beach in Sydney, the core of the Australian city’s Jewish community.

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For the second day running, President Volodymyr Zelensky of Ukraine was set to meet in Berlin with Steve Witkoff and Jared Kushner, two key Trump aides.

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Falling in love with her inspired the director Rob Reiner to give “When Harry Met Sally…” a new ending. The Reiners went on to work together on movies and political causes.

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Plus, the hunt for the gunman in a shooting at Brown University.

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José Antonio Kast, who was elected president on Sunday, is the latest conservative to rise to power promising strict law and order measures.

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The Milwaukee County judge faces federal charges, but she has maintained her innocence.

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Advocates fear damage to labor protections if the Supreme Court upholds the president’s move to control federal agency staffing.

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Across the arts, these 10 performers took a leap of faith this year and stuck the landing in a big way.

A program for deafblind children helped 3-year-old Annie Garner, born with poor vision and no ears, learn to communicate. The Trump administration cut the program’s funding over diversity goals.

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The new chancellor believes the world needs a stronger Germany. He is still navigating how to do it.

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The number of artists living in the city has declined after growing sharply between 2004 and 2019. Almost 50 arts venues have closed in the past five years.

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Tributes are pouring in for Hollywood star as investigators obtain search warrant for couple’s Los Angeles home

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A Chinese court has ordered Malaysia Airlines to pay damages for emotional distress

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A growing body of research suggests a connection between metabolism and daylight

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From author Raynor Winn’s victim mindset to exclusive interviews with family members, there’s plenty of new information about Winn and her alleged web of lies in this one-off film

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At least 15 people died in the attack on a Hanukkah event in Sydney, with the youngest victim aged just 10

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Tess Daly and Claudia Winkleman will present their final episode of Strictly this Saturday

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The 50-year-old gunman, who was fatally shot by police, had a recreational hunting licence and was a member of a gun club

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The LAPD has launched a homicide investigation after bodies of When Harry Met Sally filmmaker and his wife were found. Here’s everything we know so far

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All arrivals and departures are taking place on one runway as urgent repairs are carried out

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Paul Doyle is expected to appear for sentencing at Liverpool Crown Court this morning

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