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ZAP-X radiosurgery and ZAP-Axon SRS planning: technology overview, workflow and complex case insights from a leading SRS centre

24 décembre 2025 à 10:11

ZAP-X is a next-generation, cobalt-free, vault-free stereotactic radiosurgery system purpose-built for the brain. Delivering highly precise, non-invasive treatments with exceptionally low whole-brain and whole-body dose, ZAP-X’s gyroscopic beam delivery, refined beam geometry and fully integrated workflow enable state-of-the-art SRS without the burdens of radioactive sources or traditional radiation bunkers.

Theresa Hofman headshot
Theresa Hofman

Theresa Hofman is deputy head of medical physics at the European Radiosurgery Center Munich (ERCM), specializing in stereotactic radiosurgery with the CyberKnife and ZAP‑X systems. She has been part of the ERCM team since 2018 and has extensive clinical experience with ZAP‑X, one of the first centres worldwide to implement the technology in 2021. Since then, the team has treated more than 900 patients with ZAP‑X, and she is deeply involved in both clinical use and evaluation of its planning software.

She holds a master’s degree in physics from Ludwig Maximilian University of Munich, where she authored two first‑author publications on range verification in carbon‑ion therapy. At ERCM, she has published additional first‑author studies on CyberKnife kidney‑treatment accuracy and on comparative planning between ZAP‑X and CyberKnife. She is currently conducting further research on the latest ZAP‑X planning software. Her work is driven by the goal of advancing high‑quality radiosurgery and ensuring the best possible treatment for every patient.

The post ZAP-X radiosurgery and ZAP-Axon SRS planning: technology overview, workflow and complex case insights from a leading SRS centre appeared first on Physics World.

Bridging borders in medical physics: guidance, challenges and opportunities

10 décembre 2025 à 15:00
Book cover: Global Medical Physics: A Guide for International Collaboration
Educational aid Global Medical Physics: A Guide for International Collaboration explores the increasing role of medical physicists in international collaborations. The book comes in paperback, hardback and ebook format. An open-access ebook will be available in the near future. (Courtesy: CRC Press/Taylor & Francis)

As the world population ages and the incidence of cancer and cardiac disease grows alongside, there’s an ever-increasing need for reliable and effective diagnostics and treatments. Medical physics plays a central role in both of these areas – from the development of a suite of advanced diagnostic imaging modalities to the ongoing evolution of high-precision radiotherapy techniques.

But access to medical physics resources – whether equipment and infrastructure, education and training programmes, or the medical physicists themselves – is massively imbalanced around the world. In low- and middle-income countries (LMICs), fewer than 50% of patients have access to radiotherapy, with similar shortfalls in the availability of medical imaging equipment. Lower-income countries also have the least number of medical physicists per capita.

This disparity has led to an increasing interest in global health initiatives, with professional organizations looking to provide support to medical physicists in lower income regions. Alongside, medical physicists and other healthcare professionals seek to collaborate internationally in clinical, educational and research settings.

Successful multicultural collaborations, however, can be hindered by cultural, language and ethical barriers, as well as issues such as poor access to the internet and the latest technology advances. And medical physicists trained in high-income contexts may not always understand the circumstances and limitations of those working within lower income environments.

Aiming to overcome these obstacles, a new book entitled Global Medical Physics: A Guide for International Collaboration provides essential guidance for those looking to participate in such initiatives. The text addresses the various complexities of partnering with colleagues in different countries and working within diverse healthcare environments, encompassing clinical and educational medical physics circles, as well as research and academic environments.

“I have been involved in providing support to medical physicists in lower income contexts for a number of years, especially through the International Atomic Energy Agency (IAEA), but also through professional organizations like the American Association of Physicists in Medicine (AAPM),” explains the book’s editor Jacob Van Dyk, emeritus professor at Western University in Canada. “It is out of these experiences that I felt it might be appropriate and helpful to provide some educational materials that address these issues. The outcome was this book, with input from those with these collaborative experiences.”

Shared experience

The book brings together contributions from 34 authors across 21 countries, including both high- and low-resource settings. The authors – selected for their expertise and experience in global health and medical physics activities – provide guidelines for success, as well as noting potential barriers and concerns, on a wide range of themes targeted at multiple levels of expertise.

This guidance includes, for example: advice on how medical physicists can contribute to educational, clinical and research-based global collaborations and the associated challenges; recommendations on building global inter-institutional collaborations, covering administrative, clinical and technical challenges and ethical issues; and a case study on the Radiation Planning Assistant project, which aims to use automated contouring and treatment planning to assist radiation oncologists in LMICs.

In another chapter, the author describes the various career paths available to medical physicists, highlighting how they can help address the disparity in healthcare resources through their careers. There’s also a chapter focusing on CERN as an example of a successful collaboration engaging a worldwide community, including a discussion of CERN’s involvement in collaborative medical physics projects.

With the rapid emergence of artificial intelligence (AI) in healthcare, the book takes a look at the role of information and communication technologies and AI within global collaborations. Elsewhere, authors highlight the need for data sharing in medical physics, describing example data sharing applications and technologies.

Other chapters consider the benefits of cross-sector collaborations with industry, sustainability within global collaborations, the development of effective mentoring programmes – including a look at challenges faced by LMICs in providing effective medical physics education and training – and equity, diversity and inclusion and ethical considerations in the context of global medical physics.

The book rounds off by summarizing the key topics discussed in the earlier chapters. This information is divided into six categories: personal factors, collaboration details, project preparation, planning and execution, and post-project considerations.

“Hopefully, the book will provide an awareness of factors to consider when involved in global international collaborations, not only from a high-income perspective but also from a resource-constrained perspective,” says Van Dyk. “It was for this reason that when I invited authors to develop chapters on specific topics, they were encouraged to invite a co-author from another part of the world, so that it would broaden the depth of experience.”

The post Bridging borders in medical physics: guidance, challenges and opportunities appeared first on Physics World.

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