In an 18-month clinical trial of the experimental GLP-1 pill orforglipron, about 60 percent of people lost at least 10 percent of their body weight.

This rare planetary alignment will be visible from August 10 but will be best viewed later in the month. Here’s everything you need to know to see it at its best.

Eighty years after the dropping of the first atomic bomb, Hiroshima’s survivors and their descendants describe how health problems and stigma have echoed down the generations.

First came the idea of splitting the atom; then, a chain of events leading to a moment forever etched in collective memory—the use of nuclear weapons on Hiroshima and Nagasaki in 1945.

A report on the death of five people in the Titan submersible blames design, maintenance, and inspection flaws for its failure. “It all came back to Mr. Rush,” the head of the investigation told WIRED.

WIRED talked with one of the most influential voices in computer science about the potential for AI and quantum to supercharge supercomputers.

Potatoes as we know them today are the product of a hybridization that took place 9 million years ago between two plants, one of which was an ancestor of the tomato.

By proving how individual molecules create the complex motion of fluids, three mathematicians have illuminated why time can’t flow in reverse.

Scientists hope their plumage project could someday lead to biocompatible lasers that could safely be embedded in the human body.

With clean energy more cost-competitive than it once was, the White House’s oil-first strategy is faltering.

Evidence is growing that some HIV-infected infants, if given antiretroviral drugs early in life, are able to suppress their viral loads to undetectable levels and then come off the medicine.

Your gadgets run on direct current, but the electricity in your home is alternating current. What’s up with that?

As federal vaccine policy shifts under US health secretary Robert F. Kennedy Jr., lawmakers are looking to give state-level public health officials authority to ignore federal recommendations.

The WHO believes one in five children in Gaza are acutely malnourished, with the health effects potentially lasting for generations.

The disease has claimed the lives of 12 people in the country this year, with the virus continuing to spread rapidly.

A new Department of Energy report “fundamentally misrepresents” climate research and leaves out key context, multiple scientists cited in the report tell WIRED.

Once dismissed as just snoring, sleep apnea is now emerging as an early warning sign for serious conditions like Alzheimer’s, heart disease, and depression.

Patients with Ehlers-Danlos Syndrome are six times more at risk for the sleeping disorder. Now scientists are studying them in hopes of finding remedies beyond the CPAP machine.

Stress, isolation, and uncertainty appear to have caused the brain to age quicker for those who lived through the crisis.

New AI regulations suggested by the White House mirror changes to environmental permitting suggested by Meta and a lobbying group representing firms like Google and Amazon Web Services.

The space plane’s test flight will advance development of a new navigation technology based on electromagnetic wave interference.

Astronomers have discovered a new exoplanet that may be habitable 35 light-years from Earth. Named L 98-59 f, it joins four other worlds in the temperate zone of an intriguing planetary system.

By extending the scope of a key insight behind Fermat’s Last Theorem, four mathematicians have made great strides toward building a unifying theory of mathematics.

Mounting evidence shows no US state is safe from the flooding that ravaged Texas’ Kerr Country.