Developing lenacapavir, the drug newly approved to protect against HIV for six months in one shot, took basic science, sophisticated chemistry, and perseverance

Genetic mutations more than 20 million years ago helped birds tolerate the tart and broaden their diets

Injections of mRNA may offer a simpler, cheaper way to build powerful CAR-T cells

At long last, scientists have a nearly complete cranium from hominins known as Denisovans

Realignment of major program units aims to improve efficiency and make up for loss of federal contracts

Following criticism for all-male winners in the past, women earned two of the three Frontiers Planet Prizes this year

The Vera C. Rubin Observatory will build an unprecedented map of the universe—and discover billions of fast-changing objects

Morning agency email indicating resumption of hundreds of millions in grants is quickly undone

FDA’s approval of lenacapavir comes at a time when global health cuts could stall its rollout

Bogong moths fly 1000 kilometers orienting to stars and the Milky Way, an ability never seen before in invertebrates

A Science analysis of canceled and curtailed federal grants reveals hits to research, collections, and training

Hundreds of scientists have lost labs, equipment, and specimens

Unique ability allows the animals to protect themselves and their offspring from decaying food and other material

The pancreas, which helps control blood sugar in humans, may be critical part of shark immune system

Through two grassroots efforts, more than 80 op eds have been published in news outlets across the country

William Young calls terminations illegal, berates agency for discrimination

Drone imagery reveals ancient arena where Tyrannosaurus rex– or ostrichlike dinos may have wooed mates

Coalition offers two models it says increase accountability and reflect the “true costs” of research

Mystery signals used to locate gases in the spaces between galaxies

House panel rejects cuts to agricultural research, and Senators express doubts about cuts to NIH and forest research

Purge at immunization panel represents a major loss of expertise, as measured by scientific papers

With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses

Bombing raids target uranium enrichment facility and key personnel

Evidence of agency’s uneven guidance to employees and role of DOGE could play into legal case against cuts

U.S. should plan to build machine to hunt for new subatomic particles, National Academies report says

District judge could declare terminations unlawful—or toss suit based on technicalities

Scientists are pushing plants beyond their comfort zone to test their resilience to warming

Warming world could further heighten tensions over access to Indus River waters

Science chats with James Tabery about the overlooked role of Black prisoners in understanding the genetics of drug reactions

Government also announces cash for nuclear, carbon capture, and AI projects

Shifting production from yew trees to yeast could lead to cheaper synthesis of Taxol precursor

Newly described fossils point to ancient movement between Asia and North America

New brain-computer interface allows control of intonation, and generates a person’s voice at the speed of typical speech

Jay Bhattacharya says NIH’s final budget will be a “collaboration”

Degrading LIGO’s observations of gravitational waves would amount to “killing a newborn baby,” one astrophysicist says

Efforts to improve the rigor of research may have unwittingly handed the administration a way to attack science

Health secretary will soon name new members to expert group that recommends shots

Agency calls research to identify viral threats “unsafe”

Decline in journal revenues puts scholarships, advocacy, and other activities at risk

Macrophages help male deer build their impressive headgear, new study suggests